Other memorable guest star roles in television series include How I Met Your Mother, Angel, Smallville, Charmed, Scrubs, and Community.

He has also made small appearances in two Michael Bay films: Transformers, where he was a man being interviewed on television, and in The Island, where he portrayed a mentally underdeveloped clone.

Manoux has also provided voice work in several films and animated television shows, including Scrappy Rex and Brainiac Scooby in Scooby-Doo and Scooby-Doo 2: Monsters Unleashed and most notably as the voice of Kuzco in various Disney projects, including House of Mouse, Mickey's Magical Christmas: Snowed in at the House of Mouse, The Emperor's New School and The Emperor's New Groove: The Video Game.

He has also written for The Wayne Brady Show, The X-Fools video game, Microshaft Winblows 98 and he co-wrote the comedic circus tragedy Tights on a Wire with George Brant.

[10] In 2015, Manoux appeared in Canadian court after two people staying in his Toronto condominium discovered a home security camera and reported it to the police.