[2] She began her career in show business as a child star, and her breakthrough came when she played the title role in the soap opera Flordeluna, which aired from 1979 until 1984.

[4] In 2020, she won "Best Actress in a Drama Series" alongside Angel Locsin, Maricel Soriano and Eula Valdez at the 18th Gawad Tanglaw Awards.

The father of her child was Aga Muhlach, her screen partner in the films Erpat kong Forgets, Napakasakit Kuya Eddie, Bakit Madalas ang Tibok ng Puso, When I Fall in Love and others.

She was considered the "80s Teen Drama Princess" alongside Julie Vega, whose soap Anna Liza provided stiff competition to Flordeluna.

Her transformation from a teenage star to a serious actress started in 1989 when she topbilled Mina Films' Rosenda opposite erstwhile boyfriend Gabby Concepcion.

In 2001–2010, after her separation from husband John Estrada, she hosted the morning talk show SiS also on GMA-7 with sister Gelli de Belen and their friend Carmina Villarroel.

: Mea Culpa, various episodes of Maalaala Mo Kaya, La Vida Lena, Love in 40 Days and Dirty Linen.

[18][19] Along with her sister Gelli, and their closest friends in showbiz Carmina Villarroel and Candy Pangilinan they have a podcast called Wala Pa Kaming Title,[20] which is also available on their respective YouTube channels.