Misolas played for the Letran Knights in college, winning two back-to-back NCAA championships from 1998 to 1999 alongside Kerby Raymundo, Chris Calaguio, and Aldin Ayo.
[4] Although he was rarely used, he became a PBA champion when on Christmas Day, Coca-Cola won Game 4 and clinched the All-Filipino Cup.
[5][6] When his contract expired, Misolas left Coca-Cola to play in the Philippine Basketball League (PBL).
[17] On January 20, 2011, the management of the Energy Boosters announced that they would take a leave of absence for the 2011 Commissioner's Cup to make way for the Smart Gilas Philippine national team.
[22] In 2005, Misolas was selected to be part of the Philippine men's national basketball team pool for the 2005 SEABA Championship.