Jean Massieu (French: [ʒɑ̃ masjø]; 1772 – July 21, 1846) was a pioneering deaf educator.

One of six deaf siblings, he was denied schooling until age thirteen when he met Abbé Sicard, who enrolled him in the Institute national des jeunes sourds de Bordeaux-Gradignan, the Bordeaux School for Deaf Children.

He taught at the famous school for the deaf in Paris where Laurent Clerc was one of his students.

He began work after a scandal in Paris in Rodez[clarification needed] and dedicated his life to educating deaf children.

Jean Massieu is portrayed in the fictional film Sign Gene, the superhero film about deaf mutants who have superpowers through the use of sign language, as the fourth great-grandfather of Kate Massieu (played by Carola Insolera) the girlfriend of the leading character Tom Clerc, descendant of Laurent Clerc.