He was also a member of the Chicago Bears, Cleveland Browns, Kansas City Chiefs, Arizona Cardinals, Tennessee Titans, New Orleans Saints, Detroit Lions, and Dallas Cowboys.

One of his teammates on both the football and basketball teams was future NFL quarterback Mark Sanchez.

He was a member of the active roster for two games before he was waived and re-signed to the team's practice squad on December 11.

After spending the entire 2010 season on their practice squad, starting fullback Heath Evans retired, and Collins became the Saints' starter.

On March 19, 2014, Collins signed a one-year deal with the Detroit Lions, where his offensive coordinator was former Saints coach Joe Lombardi.