The village became "a lively emporium where Comanches brought Apache slaves, horses and mules to trade for French packs of powder, balls, knives, and textiles and for Taovaya-grown maize, melons, pumpkins, squash, and tobacco.

"[4] In 1759, in response to the destruction of the San Saba Mission, the Spanish led an expedition against the Taovaya and their allies and attacked the twin villages.

[3] After the Civil War, the Chisholm Trail, which passed through this area, was heavily used to drive cattle from Texas to markets in Kansas.

In 1892, the Chicago, Rock Island and Pacific Railway laid tracks along the trail route.

The Enid and Anadarko Railway, sold to the Rock Island in 1903, built a line from Lawton to Waurika.

At that time the southeast corner of the county extended to Mud Creek including the communities of Belleville and Courtney.

An election for the seat was held in 1908 between Ryan, Sugden and Waurika, but none of the towns won a majority.

Waurika Lake was created in 1971 by damming Beaver Creek in northwestern Jefferson County.

Despite Democrats leading in voter registration as recently as the late 2010s, Jefferson County has almost exclusively supported Republican candidates in almost every election of the 21st century.