[4] Hoffmann has held several teaching positions including California College of the Arts, the Nuova Accademia di Belle Arti and Goldsmiths, University of London, as well as others.

[5] Hoffmann trained as a theater director, studied stage directing and dramaturgy at the Ernst Busch Academy of Dramatic Arts in Berlin.

In 2012, together with Edoardo Bonaspetti, Andrea Lissoni, and Filipa Ramos, Hoffmann developed the ongoing Vdrome.org, an online platform offering screenings of films and videos directed by visual artists and filmmakers.

[19][20] In February 2014 he co-curated, with Triple Candie, I Cancel All My Works At Death, the first comprehensive survey of the actions and performances of James Lee Byars.

From 2013 to 2017 Hoffmann organized the recurring public program AM at the JM, an event that invited artists to be in conversation with the curator starting at 8am and taking place at Think Coffee at New York's Union Square every other month.

[21] Participating artists have included: Erica Baum, Brian Belott, Dara Birnbaum, Christian Boltanski, Andrea Bowers, Luis Camnitzer, Ian Cheng, Clarie Fontaine, Dani Gal, Ryan Gander, Liam Gillick, Nicolas Guaagnini, Camille Henrot, Allan McCollum, Adam McEwen, Ken Okishi, Adam Pendelton, Alix Perlstein, Walter Price, Lucy Raven, Adrian Villar Rojas, Rachel Rose, Eva Rothschild, Erin Shirreff, Taryn Simon and others.

"[22] Hoffman wrote the essay describing the exhibition "Presumed Innocence, or Fifty Shades of Green: On the Work of Anna Weyant" at the 56 Henry gallery in Manhattan that was on show from September through November 2019.

[27] Hoffmann was guest lecturer at the Nuova Accademia di Belle Arti in Milan from 2004 to 2016 [28] and associate professor at the Graduate Program in Curatorial Practice at California College of the Arts in the San Francisco Bay Area from 2006 to 2012.

[30] In 2000 Hoffmann was visiting professor at the department of Critical Writing and Curatorial Practice at Konstfack University College of Arts, Crafts and Design in Stockholm.

Among his book publications are: The Exhibitionist: A Journal on Exhibition Making was founded in 2009 by Hoffmann;[32][33] the journal has advocated the author theory as developed specifically by François Truffaut in his 1954 essay "Une certaine tendance du cinéma français" ("A certain tendency in French cinema") and adapted Truffaut's ideas to the sphere of exhibition making.

[citation needed] He has written for Parkett, Texte zur Kunst, DOMUS, and Critique d'Arts, and was a columnist for Purple from 2001 to 2003 as well as a correspondent for Flash Art from 2002 to 2007.