It hosted its first regular season game on June 20, 1995, in which major league veteran José Guillén hit a home run to ensure a SeaWolves victory over the Jamestown Jammers.

[7] In July 2015, the People for the Ethical Treatment of Animals (PETA) also ranked the stadium number five among the most vegetarian-friendly minor league ballparks.

Once the civic government secured an $8 million grant from the Commonwealth of Pennsylvania to build UPMC Park, the Welland Pirates moved to Erie.

In 1995, he established a $500,000 endowment with PNC Bank and the Erie Community Foundation to perpetually support the downtown baseball stadium.

"[6] Seating along UPMC Park's first and third base lines has a unique configuration due to the space constraints of an urban construction.

Additions included a new 40-foot (12 m) electronic scoreboard (which has a nautical theme), a two-tiered picnic area, eleven luxury box seats, and new concession stands.

[15] An additional video board was added to Erie Insurance Arena, which borders the stadium, that displays scores from other Eastern League games, player statistics, and information about the Detroit Tigers.

Happy Howler, LLC, manages the concessions at UPMC Park, offering a typical ballpark menu of hot dogs, hamburgers, nachos, and peanuts.

The SeaWolves organization repeated as champions in 2018 with their Fiesta Burger, topped with pepper jack cheese, bacon, guacamole, onion strings, and Bush's Black Beans.