James William Colborn (born May 22, 1946) is an American former Major League Baseball pitcher.

The right-handed Colborn pitched for the Chicago Cubs (1969-1971), Milwaukee Brewers (1972-1976), Kansas City Royals (1977-1978) and Seattle Mariners (1978).

Colborn was traded along with Brock Davis and Earl Stephenson to the Brewers for José Cardenal on December 3, 1971.

Over the next three seasons, however, Colborn posted losing records (10-13 in 1974, 11–13 in 1975 and 9–15 in 1976) before being traded, along with Darrell Porter, to the Kansas City Royals.

In 1977, Colborn won 18 games for a Royal team that won the second of three consecutive American League West titles (all three times, however, the Royals lost to the New York Yankees in the American League Championship Series; Colborn did not pitch in the 1977 ALCS).