Joanne's grandmother was the late pre war singer actress Naty Bernardo.

[1] She was discovered by Filipino composer-singer-manager Nonong 'Dero' Pedero in 1984, who soon took the young singer under his management, employing her talent for commercial jingles.

Prior to Lorenzana's formal foray into local Philippine entertainment, she front-acted for international acts held locally, such as Gloria Estefan and the Miami Sound Machine, Menudo (the former group of Ricky Martin) and the British jazz ensemble Shakatak.

[2] The following year, she was launched in a show billed as JoAnne: Her First Time to announce the entry of the pop artist into the music industry.

Her song "My Everyday Valentine" was co-written with Jimmy Borja, who did the music; Lorenzana started writing the lyrics in 2016.