[1] From 1955 to 1957 she was a National Science Foundation postdoctoral fellow at Yale University studying polymeric electrolytes.
In 1959, she married Arthur Mattuck, who at that point had become a professor of mathematics at the Massachusetts Institute of Technology.
Her early work at the firm concerned high-temperature oxidation and materials for the space program, focusing on the transition metals molybdenum, tungsten, and zirconium.
She headed a team which created the two volume Physical, Chemical and Biological Treatment Techniques for Industrial Wastes (1976), a survey of manufactured goods and their potential for causing pollution.
She examined limestone scrubbers that removed sulfur dioxide, demonstrated how to reduce hard deposits which hindered their effectiveness, and improved their design.
In 1959, Berkowitz married Arthur Mattuck, a high school classmate who was by that time a mathematics professor at the Massachusetts Institute of Technology.