John Wesley Hunt (1773–1849) was an American businessman, slave trader, and early civic leader in Lexington, Kentucky.
Hunt enslaved as many as 77 people, many of them children, including farm and industrial and domestic workers.
He married Catherine Grosh, and in 1814, he built a two-story brick mansion known as "Hopemont" (today known as The Hunt-Morgan House) for him and his wife.
His grandson, John Hunt Morgan, was a famous Confederate general during the American Civil War of 1861–1865.
A great-grandson, Thomas Hunt Morgan, was the first person from Kentucky to win a Nobel Prize.