DMV National University of La Plata, Argentina, 1980 Hans Sigrist Prize Jorge Enrique Galán is an Argentinian-American microbiologist who specializes in infectious disease, bacterial pathogenesis including Salmonella.
He runs the Galán Laboratory at Yale University School of Medicine which studies the "molecular mechanisms of pathogenesis of Salmonella and Campylobacter".
[They] aim to define the functional and...the atomic interface between these pathogens and their hosts and...to provide the bases for the development of novel prevention and therapeutic strategies to combat infectious diseases that are a global public health concern.
[2] Galan discovered that certain microbes use a molecular machine called a type III secretion system (T3SS, large, needle-like complexes of more than 30 proteins) to infect and replicate within eukaryotic cells.
A number of disease-causing Gram-negative bacteria, including Salmonella, Shigella, Yersinia, and Chlamydia, also deploy T3SSs, which makes the system a potential therapeutic target for the next generation of antibiotics.