Joseph Campau Street has a unique collection of buildings in southeast Michigan reflecting early 20th century commercial architecture.

[1] The street is named for Joseph Campau (February 2, 1769 – July 23, 1863) [2] who was among Detroit, Michigan's leading citizens and wealthiest landowners at the dawn of the 19th century.

[3] He made millions in the real estate industry and served in several public offices for the city.

[7] The surrounding neighborhoods were densely packed single-family homes,[8] and this section of street quickly became the second busiest shopping district in southeast Michigan, after only downtown Detroit.

The former Parke-Davis Research Laboratory, designated a National Historic Landmark, was redeveloped as a boutique luxury hotel located on the Detroit International Riverfront.