As a senior in 2010, he caught 35 passes for 558 yards and 5 touchdowns in nine games, earned first-team All-District 5-5A honors and was voted a team captain, as well as being selected Legacy's Most Valuable Player.

[1] He committed to the University of Wyoming to play college football on December 14, 2010, choosing the Cowboys over Duke and Tulsa.

[3][4] After sitting out 2012 due to NCAA transfer rules, Doctson played in 12 games with six starts in his first year at TCU in 2013.

He made his first career reception in the season opener in a 16–38 loss on Monday Night Football to the Pittsburgh Steelers.

[8] During pregame warmups in Week 3 against the New York Giants, Doctson aggravated his Achilles injury keeping him sidelined until October 21, 2016, when he was placed on injured reserve.

[13] In 2018, Doctson played in 15 games with 12 starts, finishing as the Redskins second-leading receiver with 44 catches for 532 yards and two touchdowns.

[18] He played seven snaps without making a reception in the Vikings' 27–23 comeback win over the Denver Broncos,[19] but was waived on November 26, 2019.