He graduated from the National Military College with a degree in civil engineering, was promoted as army major by 1921, and became a close associate of the War Minister, General Agustín Justo.

Appointed Director of Army Engineers upon his return, Pistarini recommended German contractors for public works in Argentina and was open regarding his Nazi and Fascist sympathies.

He was returned to the post of Minister of Public Works in March 1944 and served a brief, concurrent term as vice president following the populist Juan Perón's dismissal.

[3] Ill health led to his retirement in June 1952 and following Perón's September 1955 overthrow, he had his property seized, was stripped of rank and imprisoned in Ushuaia.

The sub-Antarctic climate in Ushuaia led to a worsening in Pistarini's health, and he was returned to Buenos Aires, where he died at a military hospital in 1956.