Antonia Minor was a niece of the first Roman Emperor Augustus and the youngest daughter of triumvir Mark Antony.

Caligula also gave them one million gold pieces, the whole amount of the revenues of Commagene during the twenty years that it had been under a Roman province.

The reasons for providing a client kingdom with such vast resources remain unclear; it was perhaps a stroke of Caligula's well-attested eccentricity.

When she died, Antiochus IV in her honor founded a town called Iotapa (modern Aytap, Turkey).

On coinage her royal title is in Greek ‘ΒΑΣΙΛΙΣΣΑ ΙΩΤΑΠΗ ΦΙΛΑΔΕΛΦΟΣ’, ‘of Queen Iotape Philadelphus’.