Juquila District is located in the center of the Costa Region of the State of Oaxaca, Mexico, on the Pacific coast.

[1] The district lies on the Pacific coast of southwestern Oaxaca, with generally hilly land rising to the southern edge of the Sierra Madre del Sur.

[2][failed verification] The most important economic activity is agriculture, including cultivation of maize, beans and vegetables for personal consumption.

The Chatino language is still widely spoken in inland communities such as San Miguel Panixtlahuaca, Santa María Temaxcaltepec and Santiago Yaitepec.

[4] The ruins of the capital of the Chatino state are preserved near Santos Reyes Nopala, and include large stone buildings, ball courts and pyramids.