57805219158ENSG00000158941ENSMUSG00000033712Q8N163Q8VDP4NM_021174NM_199205NM_001363068NM_001363069NM_001393997NM_146055NP_066997NP_001349997NP_001349998NP_666167KIAA1967, also known as Deleted in Breast Cancer 1, is a protein which in humans is encoded by the KIAA1967 gene.

[5][6][7] Recent studies show that DBC1 is an inhibitor of the sirtuin-type deacetylase, SIRT1, which deacetylates histones and p53.

[8][9] DBC1 is likely to regulate the activity of SIRT1 or related deacetylases by sensing the soluble products or substrates of the NAD-dependent deacetylation reaction.

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