The KIR genes are also extremely homologous, which means that they are similar in position, structure and evolutionary origin, but not necessarily in function.

Have the ability to lyse target cells without prior sensitization antigen and regulate the immune responses by secreting chemokine adaptive and cytokines.

[4] The genes responsible for coding of KIR proteins are found along the 19th chromosome section 19q 13.4 within the 1Mb Leukocyte Receptor Complex (LRC).

The subsets of the KIR proteins are classified by their number of extracellular IG domains and by whether they have a long (L) or short (S) cytoplasmic domain-tail.

The tyrosine kinase based transductions are enzymatic transferences of a phosphate group from an ATP molecule to a protein in the cell.