3WYR3805n/aENSG00000275699ENSG00000275317ENSG00000284509ENSG00000277750ENSG00000284365ENSG00000275848ENSG00000275456ENSG00000274955ENSG00000277964ENSG00000277362ENSG00000276979ENSG00000283961ENSG00000277850ENSG00000284460ENSG00000278074ENSG00000277076ENSG00000274189ENSG00000276044ENSG00000276779ENSG00000277355ENSG00000283869ENSG00000278201ENSG00000278271ENSG00000275237ENSG00000189013ENSG00000273498ENSG00000274193ENSG00000278430ENSG00000274232ENSG00000274609ENSG00000284013ENSG00000283986ENSG00000284340ENSG00000284562ENSG00000284206ENSG00000284457n/aQ99706n/aNM_002255NM_001080770NM_001080772NM_001258383n/aNP_001074239NP_001074241NP_002246n/aKiller cell immunoglobulin-like receptor 2DL4 is a protein that in humans is encoded by the KIR2DL4 gene.

[5] The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC).

The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

[4] The only so far reported ligand of KIR2DL4 is the non-classical HLA class 1 gene HLA-G, leading to the inhibition of the cytolytic NK cell function.

[5] This article incorporates text from the United States National Library of Medicine, which is in the public domain.