600719746ENSG00000187010ENSMUSG00000028825Q02161Q8CF94NM_001282871NM_001282872NM_016124NM_016225NM_011270NP_001269800NP_001269801NP_057208NP_035400Rh blood group, D antigen also known as Rh polypeptide 1 (RhPI) or cluster of differentiation 240D (CD240D) is a protein that in humans is encoded by the RHD gene.

[6] RHD has sequence similarity to RHCE, RhAG, RhBG, and RhCG and these five genes constitute the Rh family.

It was proposed that the erythrocyte Rh complex is a heterotrimer of RhAG, RhD, and RhCE protein subunits.

[7] RhAG is a functional ammonia transporter and is required for normal cell surface expression of RhD and RhCE.

Patients who lack RhD/RhCE/RhAG on the surface of their erythrocytes have hemolytic anemia.