TEK tyrosine kinase

4K0V, 1FVR, 2GY5, 2GY7, 2OO8, 2OSC, 2P4I, 2WQB, 3L8P, 4X3J701021687ENSG00000120156ENSMUSG00000006386Q02763Q02858NM_000459NM_001290077NM_001290078NM_001375475NM_001375476NM_001290549NM_001290551NM_013690NP_000450NP_001277006NP_001277007NP_001362404NP_001362405NP_001277478NP_001277480NP_038718Angiopoietin-1 receptor also known as CD202B (cluster of differentiation 202B) is a protein that in humans is encoded by the TEK gene.

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans.

[7] TEK has also been suggested as a marker for nucleus pulposus progenitor cells, from the intervertebral disc, which upon activation by Angiopoietin-1 starts to multiply and differentiate.

[7] In cancer patients, TEK (Tie2) is expressed in a subpopulation of monocytes that home in on the tumor and are essential for the formation of new blood vessels there.

[11] TEK tyrosine kinase has been shown to interact with: This article incorporates text from the United States National Library of Medicine, which is in the public domain.