CCR8 (gene)

123712776ENSG00000179934ENSMUSG00000042262P51685P56484NM_005201NM_007720NP_005192NP_031746Chemokine (C-C motif) receptor 8, also known as CCR8, is a protein which in humans is encoded by the CCR8 gene.

Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites.

[7] Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis.

More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.