KIR2DS4

3H8N3809n/aENSG00000275731ENSG00000273526ENSG00000275351ENSG00000274921ENSG00000277345ENSG00000276885ENSG00000284408ENSG00000274957ENSG00000276154ENSG00000284307ENSG00000283779ENSG00000274324ENSG00000221957ENSG00000274714ENSG00000274533ENSG00000276209ENSG00000276634ENSG00000276465ENSG00000274947ENSG00000283727ENSG00000283846ENSG00000276395ENSG00000275938ENSG00000284244ENSG00000284264ENSG00000283870ENSG00000283882ENSG00000276254n/aP43632Q8NHJ0n/aNM_012314NM_001281971NM_001281972n/aNP_001268900NP_001268901NP_036446NP_001268900.1n/aKiller cell immunoglobulin-like receptor 2DS4 is a protein that in humans is encoded by the KIR2DS4 gene.

The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC).

[6] KIR2DS4 has unusual HLA-I specificity binding some HLA-C allotypes and HLA-A*11.

[6] A common allele of KIR2DS4 encodes a truncated version (KIR-1D) that has no HLA-I binding ability.

[8][9][10] This article incorporates text from the United States National Library of Medicine, which is in the public domain.