3812245615ENSG00000276004ENSG00000278361ENSG00000284046ENSG00000278442ENSG00000275416ENSG00000275626ENSG00000284295ENSG00000278707ENSG00000278758ENSG00000278656ENSG00000278850ENSG00000284213ENSG00000276424ENSG00000284528ENSG00000277982ENSG00000274722ENSG00000278726ENSG00000275511ENSG00000275083ENSG00000273911ENSG00000283975ENSG00000276357ENSG00000278809ENSG00000277181ENSG00000284384ENSG00000283951ENSG00000278403ENSG00000275262ENSG00000278710ENSG00000275566ENSG00000284063ENSG00000276882ENSG00000240403ENSG00000276739ENSG00000284466ENSG00000278474ENSG00000284381ENSG00000288389ENSMUSG00000057439P43630Q8NHI6Q673W2NM_001242867NM_006737NM_177748NP_001229796NP_006728NP_001229796.1NP_808416Killer cell immunoglobulin-like receptor 3DL2 is a protein that in humans is encoded by the KIR3DL2 gene.
[5][6][7] The protein IGSF8 (Immunoglobulin superfamily member 8) has been identified as a binding partner of the KIR3DL2 receptor.
The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC).
The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
[7] This article incorporates text from the United States National Library of Medicine, which is in the public domain.