The hospital is on the Kyenjojo–Kabwoya Road, in the town of Kagadi in Kagadi District, about 93 kilometres (58 mi) south-west of Hoima Regional Referral Hospital.

[1] This is about 104 kilometres (65 mi) northwest of Mubende Regional Referral Hospital.

[2] The geographical coordinates of Kagadi General Hospital are 0°56'30.0"N, 30°48'32.0"E (Latitude:0.941661; Longitude:30.808889).

[3] Kagadi General Hospital was built and is owned by the government of Uganda.

In July 2012, the hospital experienced an outbreak of Ebola Hemorrhagic Fever.