Kami-Shakujii Station is served by the 47.5 km Seibu Shinjuku Line from Seibu-Shinjuku in Tokyo to Hon-Kawagoe in Saitama Prefecture.

The station has two island platforms serving three tracks.

Daytime inbound services generally use Platform 3.

[2] In fiscal 2013, the station was the 21st busiest on the Seibu network with an average of 43,643 passengers daily.

[3] The passenger figures for previous years are as shown below.