It is served by trains running on the private Seibu Railway's Seibu Shinjuku Line between Seibu-Shinjuku (8.5 km away) in Tokyo and Hon-Kawagoe (39 km away) in Saitama Prefecture.

Saginomiya Station opened on 16 April 1927.

[1] Station numbering was introduced on all Seibu Railway lines during fiscal 2012, with Saginomiya Station becoming "SS09".

In fiscal 2016, the station was the 31st busiest on the Seibu network with an average of 31,671 passengers daily.

[3] The passenger figures for previous years are as shown below.