Kampli has nearly 20 rice mills and agriculture is the primary economic activity.

The Tungabhadra River is a source of irrigation for most of Kampli's agricultural land.

The major local crops are paddy,[clarification needed] sugar cane, banana and coconuts.

It is a developing town, Kampli is well connected by road to Gangavathi, Hospet, Siruguppa, Kurugodu and Bellary.

Kalyana Karnataka Road Transport Corporation (KKRTC) runs a bus service to other cities and villages.