Karini (Greek: Καρήνη) is a village administratively belonging to the Municipal Unit of Mytilene[2] on the island of Lesbos, North Aegean, Greece.

[1] Karini is situated at an elevation of 80 meters and is positioned along the main road from Mytilene to Agiasos, approximately 1 kilometer west from the edge of the Ippios plain.

It occupies an exceptionally fertile narrow valley and benefits from a freshwater spring.

[3] Koldeway observed the remnants of an ancient building complex which he identified as a villa.

Within this complex, he discovered a well-fired buff vessel containing around 100 bronze coins, several depicting the head of Apollo and a four-stringed lyre on the reverse side.