The Karl Mathie House is located in Mosinee, Wisconsin.

[2] Karl Mathie was a clergyman, educator, and the first president of Wausau Sulphate Fiber Co. (later Wausau Paper),[3] which revived Mosinee's economy after Dessert's sawmill closed.

Later purchased by musician John Altenburgh.

[citation needed] The house is located along the Wisconsin River.

It was listed on the National Register of Historic Places in 1980 and on the State Register of Historic Places in 1989.