Karlievo (Bulgarian: Карлиево) is a village in western Bulgaria.

It is located in the municipality of Zlatitsa, in Sofia Province.

Karlievo is situated in a mountainous region in the Sredna Gora mountains.

The nearest village is Chelopech at 2 km to the west.

Most of the population is employed in the large copper and gold mines in the surrounding region or in Cumerio Med between Zlatitsa and Pirdop - the largest copper smelter and refinery in the Balkan peninsula.