[1] The name "Karugutu" applies to; Karugutu is located in Ntoroko District, in Western Uganda, approximately 23 kilometres (14 mi), by road, east of the town of Kibuuku, where the district headquarters are located.

[1] Karugutu is bordered by Tooro-Semliki Wildlife Reserve in Rwebisengo s/county to the north, Nombe s/County to the east, Kasitu S/county in Bughendera, Bundibugyo district to the south, Kibuuku town council and Bweramule S/County to the west.

The Environmental and Social Impact Assessment (ESIA) for the upgrade of this road was completed in 2017.

[4] The town is the location of Karugutu Training School, an alpine warfare training school, owned, maintained and operated by the Uganda People's Defence Forces (UPDF).

[5] At the end of the Second Congo War (1998-2003), Karugutu was inundated with Congolese refugees that followed the withdrawing UPDF troops.