Karuma is a settlement in the Western Region of Uganda.

[1] Karuma is in Kiryandongo District, Bunyoro sub-region.

The town is approximately 2.7 kilometres (1.7 mi), by road, north of Karuma Falls.

[2] The town is also approximately 11 kilometres (6.8 mi), by road, west of Kamdini, on the Lira–Kamdini–Karuma Road.

[3] This location is approximately 261 kilometres (162 mi) north of Kampala, Uganda's capital and largest city.,[4] The coordinates of the town are 2°15'16.0"N, 32°14'37.0"E (Latitude:2.254445; Longitude:32.243611).