[2] While serving in this role, she worked alongside D. Neil Hayes to document four molecular subtypes of squamous cell cancer for the first time.

[5] A few years later, Hoadley was a lead researcher at The Cancer Genome Atlas (TCGA) which analyzed over 3,500 tumors across 12 different tissue types to see how they compared to one another.

Upon publishing the results, researchers said the findings "could spare unnecessary treatment for those patients and help save health care dollars".

"[10] The following year, Hoadley was appointed Associate Director of Cancer Genomics for the High-Throughput Sequencing Facility and eventually named an assistant professor in UNC's Department of Genetics.

[11] During the COVID-19 pandemic in North America, Hoadley was the recipient of the Marion R. Wright Award for Scientific Excellence as "an exemplary researcher within the field of metastatic breast cancer within their first three years on faculty.