Kayque was born in Rio de Janeiro, and began his career with Nova Iguaçu at the age of eleven.
He made his first team debut with the club on 11 January 2020, coming on as a second-half substitute in a 4–0 Campeonato Carioca home routing over America-RJ.
On 5 September 2020, after five more first team appearances for Nova Iguaçu, Kayque joined Botafogo on loan until the following February, and was initially assigned to the under-20 squad.
[2] Kayque had his loan extended until the end of 2021, but suffered a thigh injury which kept him sidelined between the months of April[3] and July.
[6] On 6 September 2023, Botafogo sent Kayque on a season-long loan to recently-promoted to Belgian Pro League club RWD Molenbeek.