The Kenmore was built in 1878 by an African-American, Adam Blake (April 6, 1830 – September 7, 1881),[1] and owned by him until his death, at which time it was taken over by his widow Catherine, who continued until 1887.

Adam Blake, Jr., was considered a "worthy and respected citizen, and first-class caterer for the public"[3] and as the "richest and best-known business man of his race" in Albany County.

[6] Gangster Jack “Legs” Diamond frequented the hotel[5] and had partied at the Rain-Bo the night of his death after having been acquitted of theft in the nearby city of Troy.

The Kenmore Hotel features prominently in many of William Kennedy's books, including his novel Legs about the life of Jack Diamond.

[9] The first major event held in the building after renovation was the 13th annual conference of the Preservation League of New York State, on April 18, 1986.