The northern terminus is at Kentucky Route 620 north of Georgetown.

From US 27/68 north to US 25, KY 922 is named Oliver Lewis Way.

From US 25 north to U.S. Route 62, it is named Newtown Pike.

Between New Circle Rd (KY 4) and Interstate 75, Newtown Pike is one of the most congested routes during rush hour.

From New Circle Road, it remains a four-lane arterial until it reaches Interstate 64/75 at the northern edge of urban Lexington.