Ketocaine

Ketocaine (INN) (brand name Vericaina, former developmental code name Astra 2358 or A-2358) is an amino ether local anesthetic of the butyrophenone family used topically for pain relief.

It is marketed in Italy.

[1][2][3] Williamson ether synthesis between 2'-hydroxybutyrophenone [2887-61-8] (1) and diisopropylaminoethyl chloride hydrochloride [4261-68-1] (2) gives Ketocaine (3)..

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Synthesis: [ 4 ] Patent: [ 5 ] Prec