Kibuye is bordered by Katwe to the north, Nsambya to the east, Makindye to the south, Ndeeba to the west, and Mengo to the northwest.

This location is approximately 3 kilometres (2 mi), by road, south of Kampala's central business district.

Due to its proximity to the slum in Katwe and the business suburbs of Ndeeba and Makindye, Kibuye is a combination of these environments.

There are numerous bars, pubs and nightclubs clustered in a fairly confined area of the city.

As is the case with neighboring Katwe, Kibuye has a high crime rate.