This domain encompassed regions in present-day Wakayama and southern Mie prefectures and had a substantial income of 555,000 koku.

Tokugawa Yorinobu recruited Rōnin and raised suspicions during the Keian Incident in 1651, allegedly challenging the Shogun.

Tokugawa Yoshimune, Tsunanori's younger brother and 5th lord of the domain, became the 8th Shogun after a series of events, bringing over 200 feudal retainers from the Kishū clan to Edo.

Tokugawa Munenao, the sixth lord of the domain, who inherited the clan from the branch domain after leaving Yoshimune, overcam the financial difficulties caused by the Kyoho Famine, which lost 57% of the amount of the amount of koku, with 20,000 ryo of public money borrowed, but after that, he followed the way to make up for this budget deficit with public money.

The 11th lord of the domain, Tokugawa Nariyuki, lost his worship debt during the Tenmei era, and borrowed a new 20,000 bale from the shogunate's Osaka Kurazumemai.