Kilgore Creek is a 3.27 mi (5.26 km) long 2nd order tributary to Hyco Creek in Caswell County, North Carolina.

Kilgore Creek rises about 0.5 miles south of Leasburg, North Carolina, and then flows northerly to join Hyco Creek about 2 miles northwest of Leasburg.

[2] Kilgore Creek drains 5.63 square miles (14.6 km2) of area, receives about 46.3 in/year of precipitation, has a wetness index of 394.23, and is about 62% forested.

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