According to the Geographic Names Information System, it has also been known historically as:[1] South Hyco Creek rises about 2.5 miles southeast of Prospect Hill, North Carolina and then flows north-northeast to join the Hyco River about 3 miles east-southeast of Semora, North Carolina.

[2] South Hyco Creek drains 81.31 square miles (210.6 km2) of area, receives about 46.5 in/year of precipitation, has a wetness index of 400.00, and is about 54% forested.

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