Kimball is a city in Brule County, South Dakota, United States.

[6] Kimball was first known as Stake 48 on the Chicago, Milwaukee and St. Paul Railroad line going west out of Mitchell.

The two major fires that hit Kimball, South Dakota, were significant events in the town’s history, both causing extensive damage to its downtown area.

Due to the lack of a fully developed firefighting infrastructure, the fire spread quickly, destroying many businesses and homes in the heart of Kimball's downtown area.

This fire caused significant economic damage, but the town began to rebuild afterward.

Kimball is located just north of Interstate 90 at exit 284, the southern terminus of South Dakota Highway 45.

According to the United States Census Bureau, the city has a total area of 3.09 square miles (8.00 km2), all land.

He was "a world renowned surgeon and founder of the Ochsner Clinic and Hospital in New Orleans.

Dr. Ochsner is credited with convincing the medical world of the connection between cigarette smoking and lung cancer and heart disease.