Pukwana is a town in Brule County, South Dakota, United States.

[8] According to the United States Census Bureau, the town has a total area of 0.76 square miles (1.97 km2), all land.

[9] The population center is close to Red Lake, a prairie pothole that is listed as a National Natural Landmark.

29.6% of all households were made up of individuals, and 7% had someone living alone who was 65 years of age or older.

The racial makeup of the town was 97.21% White, 2.44% Native American, and 0.35% from two or more races.

29.3% of all households were made up of individuals, and 11.2% had someone living alone who was 65 years of age or older.

About 5.6% of families and 12.1% of the population were below the poverty line, including 17.5% of those under the age of eighteen and 9.4% of those 65 or over.