Kindler syndrome

Infants and young children with Kindler syndrome have a tendency to blister with minor trauma and are prone to sunburns.

As individuals with Kindler syndrome age, they tend to have fewer problems with blistering and photosensitivity.

[4] Kindler syndrome can affect various mucous tissues such as the mouth and eyes, which can lead to other health problems.

The KIND1 gene mutated in Kindler syndrome codes for the protein kindlin-1, which is thought to be active in the interactions between actin and the extracellular matrix (focal adhesion plaques).

[5] Treatment may involve several different types of practitioner to address the various manifestations that may occur.