The main stem of the street is 3.75-mile (6.04 km) long, and runs east-west parallel to—and one block south of—northeast Fremont Street, from the eastern edge of Irving Park to Northeast 67th Avenue.

[4] Planned improvements included a flashing beacon at the intersection with NE 33rd, which can be enabled by bicyclists and pedestrians to increase safety and maintain low vehicular traffic.

[9] The street is named after a local Native American tribe, the Klickitat, and became famous as the fictional home of the characters Henry Huggins, Ramona Quimby and Beatrice "Beezus" Quimby in a series of children's novels by Beverly Cleary.

[10] Cleary grew up on nearby Hancock Street, and said the name reminded her of "the sound of knitting needles.

"[11] There are statues of the characters in the Beverly Cleary Sculpture Garden in nearby Grant Park.