Knox Presbyterian Church is located at 4156 Sheppard Avenue East in the Agincourt neighbourhood of Toronto, Ontario, Canada.

The new congregation was initially assisted by the Minister and Elders of St. Andrew's Presbyterian Church Scarborough, but has also grown over the years; their 1950s extension is named the "John Forbes Hall" after the Minister of that era (1950–1969).

Dr. Robert P Carter (1974–1987, died August 2007), Rev Gordon Hastings (1988–1996), Reverends Dr H. Glen (Moderator of the 2000 General Assembly) and Joyce Davis (1996–2003), Dr. Jeff Loach (2004–2006), now the regional director of the Canadian Bible Society.

Dr. Ian Clark served in 2004, and returned for 2006-07, and led the Induction Service on July 29, 2007 for Rev.

There is great co-operation between the two Knox Churches, as well as other congregations in the Agincourt area with joint ministerials, and social ministries and spiritual programmes such as Alpha.