Koliganek (Central Yupik: Qalirneq) is a census-designated place (CDP) in Dillingham Census Area, Alaska, United States.

[3] The present Koliganek is the third native village to bear the name along the Nushagak River since the late 19th century.

[5] The earliest of the three was known as "Kalignak", first settled about 1870 and was located at the junction of the Nushagak and Nuyakuk Rivers.

It was later abandoned around 1940 and the residents removed to the second Koliganek, 5 miles further downstream, on the east bank across from the Napotoli Creek.

In 1965, residents decided to relocate 4 miles further downstream, to where the present Koliganek exists.

The original Koliganek, reported as "Kalignak",[6] about a dozen miles upstream at the junction of the Nushagak and Nuyakuk rivers, featured a population on the 1880 U.S. Census of 91 Inuit.